Serum .BETA.2-microglobulin in chronic liver diseases.

Serum beta2-microglobulin level is a significant predictor of mortality in maintenance haemodialysis patients.

BACKGROUND Beta(2)-microglobulin (beta(2)-M) is recognized as a surrogate marker of middle-molecule uraemic toxins and is a key component in the genesis of dialysis-associated amyloidosis. Few studies have evaluated the association of beta(2)-M levels with clinical outcome in dialyzed patients. METHODS The prognostic implication of serum beta(2)-M levels for the survival of haemodialysis pati...

Serum markers of liver fibrogenesis, and liver histology findings in patients with chronic liver diseases.

AIM OF THE STUDY Investigation of the relationships between the grade and stage of chronic liver diseases irrespective of their etiology using some novel serum markers of liver fibrogenesis, the "classical" serum markers of liver necro-inflammatory injury (such as transaminases), and the histomorphological evaluation of liver biopsies. METHODS Markers of liver fibrogenesis: serum metalloprote...

Modification of serum beta-2-microglobulin in chronic hemodialysis patients.

The role of beta2 microglobulin levels in monitoring chronic hepatitis B.

Beta2 microglobulin is one of the domains of the histocompatibility class I human leukocyte antigen (HLA) antigen. In hepatitis infection the presentation of the viral antigen on the hepatocyte in the presence of class I HLA antigens plays a significant role in the elimination of the virus. The aim of the study was to estimate the serum beta2 microglobulin levels in cases of chronic hepatitis B...

Serum beta2-microglobulin values among healthy Brazilians using a DPC IMMULITE assay.

PURPOSE The present study was designed to determine the normal range of serum beta 2-microglobulin (Sb2M) levels among healthy volunteers in Brazil. Levels of Sb2M are elevated in human immunodeficiency virus (HIV)-infected patients and have been shown to be the best predictor of HIV infection status and of some malignant disorders, especially multiple myeloma. In order to achieve its optimal u...